블로그·2026.07.31

CUREJET Hair Loss Treatment: Is There Less Pain? Including Differences from Conventional Scalp Injections

Medically reviewed by · 유화정 대표원장

CUREJET Hair Loss Treatment: Is There Less Pain? Including Differences from Conventional Scalp Injections

We provide a detailed introduction to the CUREJET treatment method, which helps ease the concerns about ‘pain’ and ‘side effects’ — the biggest obstacles when considering hair loss treatment. From the operating principle of the needle-free microjet spray method to the specific differences from conventional scalp injection treatments, as well as Modi Hair Plant’s differentiated single-agent stem cell culture medium protocol, we clearly organize the information from the perspective of specialized medical staff.

Have You Been Hesitating About Hair Loss Treatment Because of Pain and Bruising?

Hair loss has become one of the greatest appearance-related concerns for people today, regardless of gender or age. It is well known that starting treatment early when hair loss is first detected can help preserve hair follicles and maintain hair density. However, when it actually comes to visiting a clinic and deciding on scalp care or injection treatment, many people find it hard to take that step.

The biggest reasons are ‘the pain felt during the treatment process’ and ‘bruising or irritation occurring after the procedure’.

The scalp is a highly sensitive area where nerves and microscopic blood vessels are very densely distributed per unit area of the body. Therefore, even with a fine needle, a sharp, stinging pain or aching sensation can be strongly felt during the process of repeatedly puncturing the scalp surface. In addition, red marks or bruises may remain on the scalp for several days after the procedure, and inconvenience in everyday work or social activities also occurs frequently.

The innovative device that emerged to overcome these limitations of conventional scalp injection treatment and to ease the burden of pain and scalp damage that patients may feel is CUREJET.

In this article, we will explain in detail whether CUREJET really involves less pain, by what principle it delivers active ingredients deep into the scalp without a needle, and what makes it different from conventional scalp injections.

What Is CUREJET Hair Loss Treatment? (The Principle of Needle-Free Microjet Technology)

A procedure scene delivering medication to the scalp with CUREJET

CUREJET is an advanced drug delivery device that, without directly puncturing the skin or scalp surface with a needle, uses ultra-high-speed microjet pressure to allow medication to penetrate finely and precisely into the dermal layer.

1. The Core Operating Principle of the Microjet Spray Method

The core technology of CUREJET is converting liquid active ingredients into ultra-fine particles on a micro scale using air pressure and a precision control system.

  • Ultra-high-speed spraying: The medication is instantaneously sprayed onto the scalp surface at a speed too fast for the human eye to follow.
  • Passing through the epidermis and penetrating the dermal layer: Rather than a needle tearing into the skin, the finely sprayed medication particles naturally pass through the epidermal layer of the scalp and reach the dermal layer where the hair follicles are located.
  • No thermal damage or physical scarring: Because it does not use heat to penetrate the skin, there is no thermal damage, and no scars or deep wounds from needle marks remain.

2. Why Is the Depth of Drug Delivery Important in Hair Loss Treatment?

The ‘hair follicle’ and ‘dermal papilla cells’, the key structures that generate and grow hair, are located in the lower part of the dermal layer of the scalp. No matter how good a scalp nutrient or growth factor may be, simply applying it to the outer surface of the scalp makes it difficult to pass through the firm scalp barrier and reach the hair follicles.

Because CUREJET can deliver active ingredients that improve the environment around the hair follicles accurately and evenly to the targeted dermal depth, it enables a different approach to care compared with simply applying products to the scalp surface.

CUREJET Hair Loss Treatment: Is There Really Less Pain and Bruising?

CUREJET

To start with the conclusion, CUREJET treatment tends to involve less burden in terms of pain, bruising, and swelling compared with conventional needle injection treatment. The specific reasons are as follows.

1. No Sharp Needle Stimulation

In conventional injection treatment, a metal needle directly stimulates the pain receptors of the scalp. In contrast, because CUREJET has no needle, the sharp, intense stabbing pain does not occur. The sensation felt during the procedure is less like being pricked by a needle and closer to very fine air bubbles or water droplets lightly tapping the scalp.

2. Reduced Bruising and Bleeding Through Minimized Microvascular Damage

The dermal layer of the scalp contains numerous microscopic blood vessels intertwined like a net. When a needle is used, these microvessels can rupture, easily causing bleeding or bruising. Because CUREJET allows the medication to penetrate in micro-particle form, as if seeping through gaps, damage to larger blood vessels is reduced, so bleeding or bruising immediately after the procedure tends to be relatively minimal.

3. Individual Differences in Pain Sensitivity

Of course, how pain is perceived may differ depending on individual scalp sensitivity and the area where hair loss is progressing. For example, areas where the scalp is thin, such as the frontal hairline or the temporal region, may feel the light snapping sensation somewhat more sensitively than the crown area. In most cases, the procedure can be performed without separate anesthesia.

A Detailed Comparison of Conventional Scalp Injections and CUREJET Treatment

To aid understanding, we compare conventional scalp mesotherapy injection treatment, which has mainly been performed at medical institutions, with CUREJET microjet treatment by key category.

Comparison itemConventional scalp injection (needle injection method)CUREJET treatment (microjet spray method)
Drug delivery toolMetal injection needleNeedle-free high-pressure microjet nozzle
Pain during the procedureStabbing pain and aching sensation presentLight tapping-level stimulation
Bleeding/bruising after the procedureNeedle marks, minor bleeding, and bruising possibleLower likelihood of bleeding and bruising
Uniformity of drug injectionDepends on the operator’s manual skill and experienceEven spraying at a consistent depth through device control
Scalp stimulation effectRegenerative response from needle woundsPromotion of blood flow through the physical stimulation of high-pressure spraying
Application at Modi Hair PlantLimitations in controlling drug clumping and painVerified
single-agent stem cell culture medium
protocol

Why Modi Hair Plant Uses Only ‘Stem Cell Culture Medium’ in CUREJET Treatment

Stem cell culture medium

Even if the CUREJET device has excellent drug delivery capability, ultimately it is the ‘quality and composition of the medication’ that goes deep into the scalp that determines the treatment outcome.

Many clinics on the market often use a mixture of exosomes, PDRN, dutasteride, and various other growth factor agents. At Modi Hair Plant, however, we do not indiscriminately mix other ingredients during CUREJET procedures and adhere to the principle of using only a single, precisely verified ingredient: ‘stem cell culture medium’.

1. Advantages of Using Stem Cell Culture Medium Alone

Creating an environment for hair follicle cell regeneration: Stem cell culture medium contains, in high concentration, a large amount of cytokines and growth factors that help activate dermal papilla cells and support the formation of microvessels around the hair follicles.

Reducing the risk of interactions between ingredients and side effects: It reduces the possibility of chemical interference between ingredients or scalp allergic reactions that may occur when multiple agents are combined, and delivers only the pure nutritional components needed by the hair follicles.

Synergy with precision spraying: CUREJET’s high-pressure micro-spray technology distributes the particles of the stem cell culture medium evenly throughout the dermal layer without clumping, increasing the absorption rate of the medication.

2. The Dual Effect of Microjet Stimulation and Nutrient Supply

Stem cell culture medium care using CUREJET does not stop at simply delivering medication.

Physical stimulation: The fine pressure stimulation delivered to the scalp surface and dermal layer during spraying promotes microcirculation in the scalp and induces a regenerative response.

Biological nutrient supply: The stem cell culture medium penetrates into the dermal space opened by the physical stimulation, supporting the environment around the hair follicles from the roots.

Post-Treatment Care and Treatment Interval Guide for CUREJET Hair Loss Treatment

Space for stem cell culture medium care

Although CUREJET is a procedure with little skin damage, proper scalp care after the procedure and an appropriate treatment interval are key to obtaining satisfactory results.

1. Recommended Treatment Interval and Number of Sessions

The treatment plan is established individually according to the degree of hair loss progression, the dryness or oiliness of the scalp, hair thickness, and the follicle graft survival environment.

  • Initial/intensive care stage: Intensive care is generally performed once or twice at intervals of 1 to 2 weeks to promptly improve the environment around the hair follicles.
  • Maintenance care stage: After the scalp condition has stabilized, the interval is extended to about once every 3 to 4 weeks to maintain regular nutrient supply.

2. Precautions After the Procedure and Scalp Care Methods

Shampooing and washing on the day: Immediately after the procedure, on the same day it is advisable to rinse lightly with lukewarm water so as to avoid irritating the scalp as much as possible, or to blow-dry with lukewarm air at the time advised by the medical staff.

Alcohol and excessive exercise: On the day of the procedure and for 2 to 3 days afterward, refraining from excessive alcohol consumption, saunas, and vigorous exercise that cause a sensation of heat in the scalp helps calm the scalp.

UV protection: Since the scalp may become temporarily sensitive right after the procedure, it is advisable to shield it from direct sunlight with a hat or parasol during outdoor activities.

Frequently Asked Questions About CUREJET Treatment (FAQ)

Question 1. I am taking oral hair loss medication (finasteride/dutasteride). Can I undergo CUREJET treatment at the same time?

Yes, they can be used together, and complementary management can be expected. Oral hair loss medication works to inhibit the hair loss–causing factor (DHT) generated by male hormones, while CUREJET stem cell culture medium care works to supply nutrients directly to weakened hair follicles and improve the scalp environment. Since the mechanisms of action differ, combining the two treatments enables more comprehensive hair management.

Question 2. Can I receive CUREJET treatment after undergoing hair transplant surgery?

Yes, it is possible. In fact, many patients at Modi Hair Plant also undergo stem cell culture medium care in parallel. There are many cases in which CUREJET care is combined after a hair transplant to help the transplanted hair settle stably and to prevent existing hair from thinning. However, since scalp irritation must be avoided during the graft survival period immediately after surgery, the appropriate timing for care should be determined through a detailed consultation with the medical staff who performed the transplant surgery.

Question 3. How long does redness or irritation last after the procedure?

In most cases, the redness immediately after the procedure naturally subsides within a few hours, and returns to its usual state by the evening of the same day or the next morning at the latest. Since no bruising or wounds from needles remain, in most cases it does not significantly interfere with daily life or going to work.

Changes after hair follicle stem cell treatment in a man in his 30s with crown hair loss and a wide part

*This is an actual patient case of a man in his 30s with a wide part due to crown hair loss who received hair follicle stem cell treatment administered with CUREJET. Drug delivery is only part of the treatment, and results appear through the combined action of multiple treatments. Individual differences may occur.

The medical staff evaluates the patient’s condition and then decides whether it can be applied. This is not a treatment performed identically for every patient.

Would You Like to Know More About Modi Hair Plant Clinic?

▶Hair Follicle Stem Cell Treatment Principle Page

▶Customized Hair Loss Diagnosis Guide by Type Page

Created personally by Modi’s Chief Director — wondering whether you are a hair transplant case or a stem cell treatment case?


References

  • Bekkers VZ, Bik L, van Huijstee JC, Wolkerstorfer A, Prens EP, van Doorn MBA. Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology — a systematic review. Drug Deliv Transl Res. 2023;13(6):1584–1599. doi:10.1007/s13346-023-01295-x (PubMed)

The above paper is a systematic review summarizing the efficacy and safety of drug delivery using needle-free jet injectors in the field of dermatology. CUREJET itself is not a device that treats hair loss; it is used as one method of drug delivery.

This post was written directly by Modi Hair Plant Clinic in compliance with medical law for the purpose of providing medical information, and was reviewed by our medical staff. For all hair loss treatments, treatment effects and progress may vary depending on the individual patient’s scalp condition, the cause of hair loss, constitution, and health status, and temporary reactions such as irritation or redness may occur. Therefore, please make your decision only after sufficient consultation with specialized medical staff before the procedure.